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Prevent Glycation to Age-Proof your Body

Prevent Glycation to Age-Proof your Body

Glycation is known to be a significant factor in the development of age-related diseases, including atherosclerosis, heart failure, Alzheimer’s disease, complications of diabetes, cataracts, and premature aging of the skin.  Glycation, a chemical reaction between sugar and protein, results in deformed and nonfunctioning molecules.  Glycated proteins then tend to fuse together in a process known as cross-linking.  Cross-linking makes tissues in the body stiff and tough.  Organs such as the heart, eyes, and skin, which must be flexible in order to function well, are particularly vulnerable to glycation damage during aging.

Glycated proteins produce toxic advanced glycation end products (AGEs) which generate free radicals and promote inflammation.  AGEs develop from chronic consumption of high quantities of sugar and refined carbohydrates found in the typical American diet.  Furthermore, cooking foods at high temperatures results in a “browning” effect, where sugars and certain oxidized fats react with proteins to form even more AGEs in the food.  The more AGEs you make, the faster you age because glucose-modified proteins are much “stickier,” adhering to blood vessels, leading to atherosclerosis, blindness, impotence, and kidney damage.   High levels of AGEs are found in diabetics. 

The first step in reducing glycation is to decrease the amount of sugary foods (including fruit juices and all sweetened beverages), starches and refined carbohydrates (including white flour white rice, and pasta) in your diet.  Limit your total caloric intake to achieve a healthy body composition.  Avoid cooking foods at high temperatures.  Supplementing with carnosine, a naturally occurring nutrient in meat, may help protect the body’s proteins from glycation.  A dietician or physician specialized in preventive-aging medicine can provide individualized guidance.

Meet the TruWell Team

The TruWell team will guide you on your daily journey through a unique medical experience designed to help each patient reach remarkable health goals through preventive and anti-aging medicine.


Lora L Brown, MD

Fellowship-trained at the world-renowned Cleveland Clinic, Lora L. Brown, MD is a double board-certified physician, specializing in the minimally invasive, interventional treatment of pain, as well as anti-aging and regenerative medicine.

Recognized by Becker’s ASC Review as one of the Best Pain Management Physicians in America, Dr. Brown is passionate in her pursuit to alleviate chronic pain for each of her patients. She speaks and teaches nationally and internationally on several topics on pain management, and has served as lead investigator on numerous published trials for her studies in pain medicine. She served as president of the Florida chapter of American Society for Interventional Pain Physicians (ASIPP) and has served on numerous state and national boards and committees.

In addition to her dedication to helping those who suffer with pain, Dr. Brown believes that balance and wellness are crucial in the prevention of the negative side effects of aging. She is a member of the American Academy of Anti-Aging and founder of TruWell, where she personally oversees every aspect of the patient's clinical diagnosis, treatment and education.

Dr. Brown earned her medical degree at the University of Texas in San Antonio. She is certified in both pain management and anesthesia by the:

  •  American Board of Anesthesiology, with certificates in both Pain Medicine and Anesthesiology
  •  American Board of Pain Medicine
  •  American Board of Interventional Pain Physicians

Contact Dr. Brown at drbrown@tru-well.com

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